4-Thiazoleacetic acid, 2-amino-α-[(1-carboxy-1-methylethoxy)imino]-
2-Amino-((1-carboxy-1-methyl ethoxy)imino)-4-thiazoleacetic acid
CAS: 91999-75-6
Molecular Formula: C9H11N3O5S
4-Thiazoleacetic acid, 2-amino-α-[(1-carboxy-1-methylethoxy)imino]- - Names and Identifiers
4-Thiazoleacetic acid, 2-amino-α-[(1-carboxy-1-methylethoxy)imino]- - Physico-chemical Properties
| Molecular Formula | C9H11N3O5S |
| Molar Mass | 273.26 |
| Density | 1.61±0.1 g/cm3(Predicted) |
| Boling Point | 541.5±56.0 °C(Predicted) |
| pKa | 1.98±0.41(Predicted) |
4-Thiazoleacetic acid, 2-amino-α-[(1-carboxy-1-methylethoxy)imino]- - References
| use | ceftazidime intermediate. |
| Production method | Ethyl acetoacetate is nitrated and chlorinated (on the acetyl group), and then cyclized with thiourea to generate α-(hydroxyimino)-2-aminothiazole acetic acid, which is then reacted with tert-butyl bromoisobutyrate and hydrolyzed to obtain the product. |
Last Update：2024-04-09 18:58:34
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